SNP screening of the HSD3B1 gene and its association with laying performance in Taihang chickens

The 3 beta- and steroid delta-isomerase 1 (HSD3B1) gene has a great influence on reproductive traits therefore been widely studied. However, little is known about the relationships between polymorphisms of HSD3B1 laying in Taihang chickens. Therefore, was selected for polymorphism detection analysis its relationship with performance traits. mRNA expression levels 16 tissues chickens were detected, SNP screened genotyped, associated results showed that expressed. level highest F1 follicles, lowest small white differentially expressed large follicles yellow follicles. C274T allele moderately polymorphic chickens, age opening day significantly earlier CC genotype than other genotypes. present demonstrate homozygous can be considered molecular marker-assisted selection (MAS) to improve breeding efficiency